SCHEMBL48367

SCHEMBL48367

O=C1NCC(O)C(=O)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27867560 0.75
SCHEMBL13811599 0.75
SCHEMBL6097795 0.70
SCHEMBL29626444 0.70
SCHEMBL48294 0.70
SCHEMBL15778628 0.70
SCHEMBL2466350 0.70
SCHEMBL16349234 0.70
SCHEMBL4316335 0.70
SCHEMBL4997881 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1419247-B1 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS DIREVO BIOTECH AG (DE) 2006-09-20 EP claimed
EP-1579015-A4 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL APPLERA CORP (US) 2006-06-21 EP claimed
EP-1579015-A2 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL Applera Corporation (US) 2005-09-28 EP claimed
EP-1579015-A3 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL Applera Corporation (US) 2005-08-25 EP claimed
US-20050130142-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids DIREVO BIOTECH AG (DE) 2005-06-16 US claimed
US-20040023220-A1 Integrated method for PCR cleanup and oligonucleotide removal APPLIED BIOSYSTEMS, LLC 2004-02-05 US claimed
WO-2004009851-A2 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL APPLERA CORPORATION (US) 2004-01-29 WO claimed
EP-1281757-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids Direvo Biotech AG (DE) 2003-02-05 EP claimed
EP-4735621-A1 NUCLEIC ACID SYNTHESIS ON REUSABLE SUPPORT DNA Script (FR) 2026-05-06 EP disclosed
EP-4665866-A1 REAGENTS AND METHODS FOR NORMALIZATION Twist Bioscience Corporation (US) 2025-12-24 EP disclosed
US-20250369027-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS TWIST BIOSCIENCE CORP (US) 2025-12-04 US disclosed
EP-4655411-A2 ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDE PROBES DNA Script (FR) 2025-12-03 EP disclosed
US-12421628-B2 Massively parallel enzymatic synthesis of nucleic acid strands DNA SCRIPT (FR) 2025-09-23 US disclosed
US-20250215617-A1 MASSIVELY PARALLEL ENZYMATIC SYNTHESIS OF NUCLEIC ACID STRANDS DNA SCRIPT (FR) 2025-07-03 US disclosed
EP-1419247-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS Direvo Biotech AG (DE) 2004-05-19 EP disclosed
US-20040023220-A1 Integrated method for PCR cleanup and oligonucleotide removal APPLIED BIOSYSTEMS, LLC 2004-02-05 US disclosed
WO-2004009851-A2 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL APPLERA CORPORATION (US) 2004-01-29 WO disclosed
WO-2003012100-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS DIREVO BIOTECH AG (DE) 2003-02-13 WO disclosed
EP-1281757-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids Direvo Biotech AG (DE) 2003-02-05 EP disclosed
WO-1999050447-A1 METHOD AND NUCLEIC ACID COMPOUND FOR BREAKING DOWN NUCLEIC ACID MOLECULES SYNTHESIZED $i(IN VITRO) MIRA DIAGNOSTIKA GMBH (DE) 1999-10-07 WO disclosed