SCHEMBL483676

SCHEMBL483676

CCC1(C(=O)NC)CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CETP P11597 6/20 0.49
CYP2C19 P33261 1/20 0.39
CYP3A4 P08684 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
P2RX7 Q99572 1/20 0.37
MME P08473 4/20 0.37
CNR2 P34972 2/20 0.36
MMP1 P03956 1/20 0.35
CNR1 P21554 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12527553 0.93 CETP (0.42) CETPCYP2C19CYP3A4SMN1; SMN2P2RX7
SCHEMBL15473885 0.89
SCHEMBL8263631 0.83 CETP (0.49) CETPCYP2C19MMECNR2CNR1
SCHEMBL4125078 0.83 CYP2C19 (0.39) CETPCYP2C19CYP3A4SMN1; SMN2P2RX7
SCHEMBL4436301 0.81 SMN1; SMN2 (0.44) CETPCYP2C19CYP3A4SMN1; SMN2P2RX7
SCHEMBL11291527 0.81 CETP (0.47) CETPCYP2C19MMECNR2CNR1
SCHEMBL11300362 0.81 CETP (0.47) CETPCYP2C19MMECNR2CNR1
SCHEMBL16416206 0.78 CETP (0.45) CETPCYP2C19SMN1; SMN2MMEMMP1
SCHEMBL22826696 0.77 MME (0.51) CETPCYP2C19MMEMMP1
SCHEMBL21249087 0.76 CETP (0.44) CETPCYP2C19MMECNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115317603-A Antibody adjuvant conjugates 小利兰·斯坦福大学托管委员会 2022-11-11 CN disclosed
CN-109843327-B Antibody adjuvant conjugates 小利兰·斯坦福大学托管委员会 2022-05-13 CN disclosed
EP-2411521-A1 COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS The Board of Regents of The University of Texas System (US) 2012-02-01 EP disclosed
WO-2010111485-A1 COMPOSITIONS FOR STIMULATION OF MAMMALIAN INNATE IMMUNE RESISTANCE TO PATHOGENS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-09-30 WO disclosed