Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842957 | 0.91 | JAK1 (0.40) | KDM4EHDAC6HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL4844208 | 0.90 | CYP3A4 (0.46) | KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4839525 | 0.89 | HDAC6 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL4840737 | 0.89 | HDAC6 (0.44) | KDM4EHDAC6HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL5261300 | 0.88 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2AHDAC6 | |
| Trifluoroacetic Acid SCHEMBL4842803 | 0.87 | KMT2A (0.45) | KDM4EMEN1KMT2AHDAC6HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4840800 | 0.87 | CHEK2 (0.45) | IKBKETBK1 | |
| Trifluoroacetic Acid SCHEMBL4842876 | 0.86 | CHEK2 (0.45) | KDM4EALDH1A1IKBKEAURKBTBK1 | |
| Trifluoroacetic Acid SCHEMBL4835096 | 0.86 | TAAR1 (0.48) | KMT2AHDAC6HDAC3HDAC4HDAC1 | |
| Trifluoroacetic Acid SCHEMBL4844131 | 0.86 | HDAC6 (0.39) | ALDH1A1KMT2AHDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | KDM4E 2903/4885MEN1 2592/4885ALDH1A1 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.