Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NCF1 | P14598 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403454 | 0.89 | APP (0.54) | APPMAPTNCF1MAOAMAOB | |
| SCHEMBL483977 | 0.88 | APP (0.65) | APPMAPTNCF1 | |
| SCHEMBL21974441 | 0.85 | APP (0.50) | APPMAPTNCF1MAOAMAOB | |
| SCHEMBL483978 | 0.84 | APP (0.52) | APPMAPTNCF1MAOB | |
| SCHEMBL22907228 | 0.82 | APP (0.49) | APPMAPTNCF1MAOAMAOB | |
| SCHEMBL18065066 | 0.81 | APP (0.58) | APPMAPTNCF1MAOAMAOB | |
| SCHEMBL20129292 | 0.81 | APP (0.47) | APPMAPTNCF1MAOBMIF | |
| SCHEMBL12324100 | 0.80 | CA12 (0.48) | APPMAPTNCF1MAOB | |
| SCHEMBL22907225 | 0.78 | APP (0.47) | APPMAPTMAOBMIF | |
| SCHEMBL2162844 | 0.77 | APP (0.57) | APPMAPTNCF1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411057-A2 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | Siemens Medical Solutions USA, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |