Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18595785 | 1.00 | NPC1 (0.46) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL28121808 | 0.90 | NPC1 (0.47) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL28121806 | 0.90 | NPC1 (0.47) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL15618877 | 0.90 | NPC1 (0.47) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL15618875 | 0.90 | NPC1 (0.47) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL483627 | 0.86 | NPC1 (0.43) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL483637 | 0.86 | NPC1 (0.45) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL483962 | 0.85 | NPC1 (0.43) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL483960 | 0.85 | NPC1 (0.43) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL8425426 | 0.85 | NPC1 (0.50) | NPC1HPGDRAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072505-B1 | A process for the preparation of oxazolidinone derivatives | DIPHARMA FRANCIS SRL (IT) | 2012-02-01 | — | — | EP | claimed |