Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 11/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.62 |
| ▸ | SCN4A | P35499 | 1/20 | 0.62 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.62 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.62 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.62 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.62 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483157 | 1.00 | SCN3A (0.62) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL483221 | 1.00 | SCN3A (0.62) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| Hydrochloric Acid SCHEMBL483509 | 0.99 | SCN3A (0.63) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL483705 | 0.85 | KCNH2 (0.63) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL483476 | 0.85 | KCNH2 (0.58) | SCN3AKCNH2MAOBPARP10OPRM1 | |
| SCHEMBL483623 | 0.84 | SCN3A (0.61) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL483864 | 0.84 | KCNH2 (0.68) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL483250 | 0.84 | KCNH2 (0.58) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL1092326 | 0.84 | KCNH2 (0.58) | SCN3AKCNH2SCN9ASCN1ASCN4A | |
| Hydrochloric Acid SCHEMBL1093198 | 0.84 | SCN3A (0.62) | SCN3AKCNH2SCN9ASCN1ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934176-B1 | QUATERNARY ALPHA-AMINOCARBOXAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS | GLAXO GROUP LTD (GB) | 2012-02-01 | — | — | EP | claimed |