Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281633 | 0.79 | SCN9A (0.57) | SCN9A | |
| SCHEMBL281365 | 0.74 | SCN9A (0.57) | SCN9A | |
| SCHEMBL3335377 | 0.73 | SCN9A (0.40) | SCN9AALDH1A1 | |
| SCHEMBL281495 | 0.73 | SCN9A (0.58) | SCN9A | |
| SCHEMBL281250 | 0.72 | SCN9A (0.56) | SCN9A | |
| SCHEMBL281466 | 0.70 | SCN9A (0.60) | SCN9A | |
| SCHEMBL281160 | 0.69 | SCN9A (0.61) | SCN9A | |
| SCHEMBL281891 | 0.69 | SCN9A (0.59) | SCN9A | |
| SCHEMBL281050 | 0.66 | SCN9A (0.59) | SCN9A | |
| SCHEMBL281482 | 0.66 | SCN9A (0.64) | SCN9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888595-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-02-01 | — | — | EP | claimed |