SCHEMBL4843328

SCHEMBL4843328

O=P(Nc1ccc(O)cc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.76
LMNA P02545 3/20 0.55
HTT P42858 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
HCRTR1 O43613 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
PKM P14618 1/20 0.50
SRC P12931 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132235 0.91 KDM4E (0.92) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL7734146 0.87 KDM4E (1.00) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL7740473 0.84 KDM4E (0.79) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL10886221 0.84 KDM4E (0.85) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL28665411 0.82 KDM4E (0.76) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL4840785 0.81 KDM4E (0.69) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL28929744 0.81 HTT (0.76) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL10051658 0.79 KDM4E (0.76) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL21234567 0.78 KDM4E (0.69) KDM4ELMNAHTTL3MBTL1HCRTR1
SCHEMBL21234321 0.78 KDM4E (0.69) KDM4ELMNAHTTL3MBTL1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7332229-B2 Varnish, shaped item, electrical insulating film, laminate, flame retardant slurry and process for producing flame retardant particles and varnish ZEON CORPORATION (JP) 2008-02-19 US disclosed
US-20050159509-A1 Varnish, shaped item, electrical insulating film, laminate, flame retardant slurry and process for producing flame retardant particles and varnish ZEON CORPORATION (JP) 2005-07-21 US disclosed