Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779273 | 0.94 | MCHR1 (0.59) | MCHR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL14290887 | 0.94 | MCHR1 (0.59) | MCHR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL4797658 | 0.94 | MCHR1 (0.62) | MCHR1ALDH1A1DRD4KMT2AMEN1 | |
| SCHEMBL14290988 | 0.89 | MCHR1 (0.63) | MCHR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14290836 | 0.87 | MCHR1 (0.54) | MCHR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14290835 | 0.87 | MCHR1 (0.54) | MCHR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14290598 | 0.84 | MCHR1 (0.51) | MCHR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14290889 | 0.84 | MCHR1 (0.51) | MCHR1ALDH1A1POLB | |
| SCHEMBL14290826 | 0.83 | MCHR1 (0.56) | MCHR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL14290928 | 0.83 | MCHR1 (0.56) | MCHR1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |