Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842888 | 0.91 | MAPK14 (0.41) | MAPK14MAPK11CTSADGAT2LPAR2 | |
| SCHEMBL4837625 | 0.91 | MAPK14 (0.39) | MAPK14MAPK11CTSADGAT2LPAR2 | |
| SCHEMBL14019008 | 0.91 | MAPK14 (0.39) | MAPK14MAPK11CTSADGAT2LPAR2 | |
| SCHEMBL14019012 | 0.91 | MAPK14 (0.41) | MAPK14MAPK11CTSADGAT2LPAR2 | |
| SCHEMBL4842004 | 0.85 | MAPK14 (0.40) | MAPK14MAPK11CTSADGAT2LPAR2 | |
| SCHEMBL4837496 | 0.85 | MAPK14 (0.42) | MAPK14MAPK11CTSALPAR2 | |
| SCHEMBL14018995 | 0.85 | MAPK14 (0.42) | MAPK14MAPK11CTSALPAR2 | |
| SCHEMBL14018785 | 0.84 | MAPK14 (0.45) | MAPK14MAPK11 | |
| SCHEMBL4840856 | 0.84 | MAPK14 (0.45) | MAPK14MAPK11 | |
| SCHEMBL4832594 | 0.84 | MAPK14 (0.42) | MAPK14MAPK11CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435731-B2 | Substituted pyrazolo[3,4-d]pyrimadines and methods of using the same | ROCHE PALO ALTO LLC (US) | 2008-10-14 | — | — | US | claimed |