Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 15/20 | 0.75 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304352 | 0.91 | BDKRB1 (0.61) | BDKRB1NISCHKDM4E | |
| Safotibant SCHEMBL1723565 | 0.85 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4030095 | 0.83 | BDKRB1 (0.74) | BDKRB1NISCH | |
| SCHEMBL12020596 | 0.81 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL4036844 | 0.79 | BDKRB1 (1.00) | BDKRB1NISCH | |
| SCHEMBL4924234 | 0.79 | BDKRB1 (0.69) | BDKRB1NISCH | |
| SCHEMBL14304935 | 0.79 | BDKRB1 (0.48) | BDKRB1 | |
| SCHEMBL4031819 | 0.78 | BDKRB1 (0.81) | BDKRB1NISCHKDM4E | |
| SCHEMBL4036840 | 0.78 | BDKRB1 (0.74) | BDKRB1NISCH | |
| SCHEMBL2568098 | 0.77 | BDKRB1 (0.64) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002849-A2 | ARYL SULFONES | NEUROGEN CORPORATION (US) | 2008-01-03 | — | — | WO | claimed |