⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL575072 | 1.00 | CHRNA7 (0.39) | — | |
| Hydrochloric Acid SCHEMBL9098929 | 0.96 | — | — | |
| SCHEMBL575245 | 0.86 | CHRNA7 (0.33) | — | |
| SCHEMBL575435 | 0.84 | — | — | |
| SCHEMBL9864651 | 0.84 | — | — | |
| SCHEMBL17550748 | 0.84 | CHRNA7 (0.36) | — | |
| SCHEMBL575736 | 0.83 | CHRNA7 (0.37) | — | |
| Hydrochloric Acid SCHEMBL15366520 | 0.81 | CHRNA7 (0.34) | — | |
| Water SCHEMBL16297127 | 0.81 | CHRNA7 (0.34) | — | |
| SCHEMBL2865219 | 0.81 | CHRNA7 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934594-B1 | CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITIES . | ALMIRALL SA (ES) | 2019-09-04 | — | — | EP | disclosed |
| CN-105142673-B | Novel cyclohexyl and quininuclidinyl carbamate derivatives with beta 2-adrenergic activator and M3 muscarinic antagonists activity | 阿尔米雷尔有限公司 | 2018-01-05 | — | — | CN | disclosed |
| US-9518050-B2 | Cyclohexyl and quinuclidinyl carbamate derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activity | ALMIRALL, S.A. (ES) | 2016-12-13 | — | — | US | disclosed |
| CN-105142673-A | New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activity | ALMIRALL SA | 2015-12-09 | — | — | CN | disclosed |
| US-20150329535-A1 | NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY | ALMIRALL, S.A. (ES) | 2015-11-19 | — | — | US | disclosed |
| EP-2934594-A1 | NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY | Almirall, S.A. (ES) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095920-A1 | NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY | ALMIRALL, S.A. (ES) | 2014-06-26 | — | — | WO | disclosed |
| US-7318477-B2 | Method and composition for cleaning a well bore prior to cementing | AKZO NOBEL N.V. (NL) | 2008-01-15 | — | — | US | disclosed |
| US-7238801-B2 | Phthalocyanine compound, method for production thereof, and near infrared absorbing dye and near infrared absorbing filter using same | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20060254770-A1 | Method and composition for cleaning a well bore prior to cementing | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2006-11-16 | — | — | US | disclosed |
| US-20030234995-A1 | Phthalocyanine compound, method for production thereof, and near infrared absorbing dye and near infrared absorbing filter using same | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-12-25 | — | — | US | disclosed |
| US-6196320-B1 | Method of cleaning a well bore prior to installing a water based fluid system | DEEP SOUTH CHEMICAL, INC. | 2001-03-06 | — | — | US | disclosed |
| WO-2000057023-A1 | METHOD OF CLEANING A WELL BORE PRIOR TO INSTALLING A WATER BASED FLUID SYSTEM | DEEP SOUTH CHEMICAL, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| WO-1999037884-A1 | METHOD OF CLEANING A WELL BORE PRIOR TO CEMENTING | DEEP SOUTH CHEMICAL, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-5904208-A | Method of cleaning a well bore prior to cementing | DEEP SOUTH CHEMICAL (US) | 1999-05-18 | — | — | US | disclosed |
| WO-1999002577-A1 | MODIFIED PHENOL-FORMALDEHYDE RESIN AND PROCESS OF MAKING THE SAME | PERSTORP AB (SE) | 1999-01-21 | — | — | WO | disclosed |
| US-5026897-A | Chemically mask cholinesterase enzymes; antispasmotic agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1991-06-25 | — | — | US | disclosed |
| US-4973734-A | ANTIDIOTE FOR ORGANOPPHOSPHATE POISONING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0220988-B1 | PROCESS FOR CULTURING BABESIA CANIS, USE IN THE PREPARATION OF ANTIGENS AND VACCINES, AND ANTIGENS AND VACCINES AGAINST PIROPLASMOSIS | RHONE MERIEUX (FR) | 1990-05-30 | — | — | EP | disclosed |
| EP-0220988-A1 | Process for culturing Babesia canis, use in the preparation of antigens and vaccines, and antigens and vaccines against piroplasmosis | RHONE MERIEUX (FR) | 1987-05-06 | — | — | EP | disclosed |