Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851642 | 0.85 | MAOB (0.44) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL11475385 | 0.81 | KDM4E (0.39) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL12936636 | 0.80 | TAAR1 (0.43) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL13884107 | 0.80 | MAOB (0.37) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL24735105 | 0.79 | TAAR1 (0.40) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL19122453 | 0.78 | KDM4E (0.42) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL608533 | 0.76 | MAOB (0.49) | MAOBTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL15225880 | 0.76 | MAOB (0.42) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL24858294 | 0.75 | MAOB (0.43) | MAOBFFAR1TAAR1KDM4EADRA2A | |
| SCHEMBL15013883 | 0.75 | RCE1 (0.54) | ALDH1A1TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432087-B2 | Method for preparing (2S, 3R, 4S)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2008-10-07 | — | — | US | disclosed |
| US-20050079587-A1 | Method for preparing (2S, 3R, 4S) -4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE | 2005-04-14 | — | — | US | disclosed |
| US-20030219880-A1 | Method for preparing (2s,3r,4s)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-11-27 | — | — | US | disclosed |