SCHEMBL4846104

SCHEMBL4846104

C/C=C\C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1968046 1.00
SCHEMBL244754 1.00
Hydrochloric Acid SCHEMBL11435828 0.93
SCHEMBL2398235 0.75
SCHEMBL27573931 0.73
SCHEMBL501453 0.72
SCHEMBL501452 0.72
SCHEMBL13451383 0.72
SCHEMBL11315909 0.71
SCHEMBL11315912 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1625116-A1 PROCESS FOR THE PREPARATION OF CARBOSTYRIL DERIVATIVES,SUCH AS ARIPIPRAZOLE AND ITS INTERMEDIATES Delmar Chemicals Inc. (CA) 2006-02-15 EP claimed
WO-2004099152-A1 PROCESS FOR THE PREPARATION OF CARBOSTYRIL DERIVATIVES, SUCH AS ARIPIPRAZOLE AND ITS INTERMEDIATES DELMAR CHEMICALS INC. (CA) 2004-11-18 WO claimed
EP-1636243-B1 CHIRAL LIGANDS FOR APPLICATION IN ASYMMETRIC SYNTHESES BOEHRINGER INGELHEIM INT (DE) 2013-11-06 EP disclosed
WO-2012079011-A1 PURIFICATION OF CIS-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE VIA EXTRACTIVE DISTILLATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-14 WO disclosed
US-7396947-B2 Chiral ligands for application in asymmetric syntheses LANXESS DEUTSCHLAND GMBH (DE) 2008-07-08 US disclosed
US-20070004927-A1 Chiral ligands for application in asymmetric syntheses BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-01-04 US disclosed
US-20060161022-A1 Chiral ligands for application in asymmetric syntheses LANXESS DEUTSCHLAND GMBH (DE) 2006-07-20 US disclosed
EP-1636243-A2 CHIRAL LIGANDS FOR APPLICATION IN ASYMMETRIC SYNTHESES LANXESS Deutschland GmbH (DE) 2006-03-22 EP disclosed
EP-1625116-A1 PROCESS FOR THE PREPARATION OF CARBOSTYRIL DERIVATIVES,SUCH AS ARIPIPRAZOLE AND ITS INTERMEDIATES Delmar Chemicals Inc. (CA) 2006-02-15 EP disclosed
WO-2004111063-A2 CHIRAL LIGANDS FOR APPLICATION IN ASYMMETRIC SYNTHESES LANXESS DEUTSCHLAND GMBH (DE) 2004-12-23 WO disclosed
WO-2004099152-A1 PROCESS FOR THE PREPARATION OF CARBOSTYRIL DERIVATIVES, SUCH AS ARIPIPRAZOLE AND ITS INTERMEDIATES DELMAR CHEMICALS INC. (CA) 2004-11-18 WO disclosed
EP-1180108-A2 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-02-20 EP disclosed
WO-2000071554-A2 IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-11-30 WO disclosed
EP-0269109-B1 PROCESS FOR THE PREPARATION OF DIALKYL 2-VINYLCYCLOPROPANE-1,1-DICARBOXYLATES HENKEL CORPORATION (US) 1992-08-26 EP disclosed
EP-0270006-B1 EFFICIENT CIS-TO-TRANS ISOMERIZATION OF 1, 4-DIHALOBUTENE-2 HENKEL CORPORATION (US) 1991-02-27 EP disclosed
US-4781807-A HYDROGEN BROMIDE CATALYST NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1988-11-01 US disclosed
EP-0270006-A1 Efficient cis-to-trans isomerization of 1, 4-dihalobutene-2 HENKEL CORPORATION (US) 1988-06-08 EP disclosed
US-4713479-A Synthesis of high-purity dialkyl 2-vinylcyclopropane-1,1-dicarboxylate NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1987-12-15 US disclosed