SCHEMBL4846970

SCHEMBL4846970

CCCCCn1cnc2nc(N)nc(F)c21

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.42
KMT2A Q03164 1/20 0.42
TLR8 Q9NR97 11/20 0.42
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TLR7 Q9NYK1 3/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850257 0.83 ADORA2A (0.42) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL4849129 0.83 ADORA2A (0.42) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL4846999 0.83 ADORA2A (0.42) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL4848376 0.77 CDK1 (0.50) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL9037728 0.73 ADORA2A (0.48) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL9039047 0.73 ADORA2A (0.48) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL9037892 0.73 ADORA2A (0.48) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL9039768 0.73 ADORA2A (0.48) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL9039048 0.73 ADORA2A (0.48) ADORA2AKMT2ATLR8ALDH1A1TDP1
SCHEMBL9041739 0.73 ADORA2A (0.48) ADORA2AKMT2ATLR8ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7321035-B2 Process for producing 2,6-dihalogenopurine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-22 US disclosed
EP-1375502-B1 PROCESS FOR PRODUCING 2,6-DIHALOGENOPURINE SUMITOMO CHEMICAL CO (JP) 2007-06-13 EP disclosed
US-6936713-B2 Process for producing 2,6-dihalogenopurine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-08-30 US disclosed
US-20050090666-A1 Process for producing 2,6-dihalogenopurine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-28 US disclosed
EP-1375502-A1 PROCESS FOR PRODUCING 2,6-DIHALOGENOPURINE SUMIKA FINE CHEMICALS Co., Ltd. (JP) 2004-01-02 EP disclosed
US-20030144508-A1 Process for producing 2,6-dihalogenopurine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-31 US disclosed