Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024 | 0.84 | — | — | |
| SCHEMBL28788726 | 0.84 | CYP3A4 (0.72) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| SCHEMBL29440219 | 0.84 | — | — | |
| SCHEMBL9421183 | 0.84 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| Trimethylammonium SCHEMBL5082654 | 0.82 | CYP3A4 (0.62) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2188812 | 0.82 | CYP3A4 (0.68) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| Bromide SCHEMBL3979509 | 0.82 | CYP3A4 (0.68) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6098611 | 0.82 | CYP3A4 (0.68) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8460462 | 0.82 | CYP3A4 (0.68) | CYP3A4TSHRPIK3CACD44ALDH1A1 | |
| SCHEMBL8218942 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076030-A2 | Substituted amide derivatives, processes for preparing them, pesticidal compositions containing them and processes for combating unwanted vegetation and fungi | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-06 | — | — | EP | claimed |
| US-4058660-A | Process for the conversion of 6-aminopenicillanic acid (6-APA) in 7-aminodesacetoxycephalosporanic acid (7-ADCA) | PALOMO COLL A L | 1977-11-15 | — | — | US | claimed |
| US-7427634-B2 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-23 | — | — | US | disclosed |
| US-6903119-B1 | Amino acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-07 | — | — | US | disclosed |
| US-20050009890-A1 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | ONO PHARMACEUTICAL CO., LTD. | 2005-01-13 | — | — | US | disclosed |
| EP-1097929-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| US-5583216-A | Methods for the manufacture of cephems | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| CN-1025031-C | 2-oxo-3,8-diaza-spiro [4,5] decane derivatives, pharmaceutical compositions containing such derivatives and process for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1994-06-15 | — | — | CN | disclosed |
| CN-1049349-A | New 2-oxo-3,8-diaza spiro [4,5] decane derivative contains formula of medicine of these derivatives and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1991-02-20 | — | — | CN | disclosed |
| US-4973684-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4914225-A | MOLDING MATERIALS, COATINGS, ADHESIVES | NIPPON PAINT CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4343618-A | Mothproofing agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1982-08-10 | — | — | US | disclosed |
| US-4303652-A | Fiber-reactive phosphorus mothproofing agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-12-01 | — | — | US | disclosed |
| US-4298606-A | Thiazolylacetamido compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4268665-A | Derivatives of antibiotic tylosin | TOYO JOZO KABUSHIKI KAISHA (JP) | 1981-05-19 | — | — | US | disclosed |
| US-4205180-A | CHEMICAL INTERMEDIATES FOR NOVEL CEPHALOSPORIN COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-05-27 | — | — | US | disclosed |
| US-4203899-A | Thiazolylacetamido compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4200640-A | TREATING CIRCULATORY DISEASES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-04-29 | — | — | US | disclosed |
| US-4098888-A | THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-07-04 | — | — | US | disclosed |
| US-3995059-A | CHOLESTEROL LOWERING AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009890-A1 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | CACNA1I, CACNA1B, CACNA1A | CYP3A4 4597/4885TSHR 4794/4885PIK3CA 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.