⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680601 | 1.00 | — | — | |
| SCHEMBL13512984 | 1.00 | — | — | |
| SCHEMBL13502507 | 1.00 | — | — | |
| SCHEMBL13512999 | 1.00 | — | — | |
| SCHEMBL4851097 | 1.00 | — | — | |
| SCHEMBL14064926 | 1.00 | — | — | |
| SCHEMBL14064983 | 1.00 | — | — | |
| SCHEMBL14064938 | 1.00 | — | — | |
| SCHEMBL13512979 | 1.00 | — | — | |
| SCHEMBL14420269 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432087-B2 | Method for preparing (2S, 3R, 4S)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2008-10-07 | — | — | US | disclosed |
| US-7420087-B2 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-09-02 | — | — | US | disclosed |
| US-7420087-B2 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-09-02 | — | — | US | disclosed |
| US-20050079587-A1 | Method for preparing (2S, 3R, 4S) -4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE | 2005-04-14 | — | — | US | disclosed |
| US-20030219880-A1 | Method for preparing (2s,3r,4s)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-11-27 | — | — | US | disclosed |