Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.64 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736385 | 0.84 | CHRM3 (0.63) | CHRM3KCNN4 | |
| SCHEMBL1682974 | 0.82 | CHRM3 (0.61) | CHRM3KCNN4 | |
| SCHEMBL2014133 | 0.82 | CHRM3 (0.61) | CHRM3KCNN4 | |
| SCHEMBL2126929 | 0.82 | CHRM3 (0.61) | CHRM3KCNN4 | |
| SCHEMBL2127682 | 0.82 | CHRM3 (0.61) | CHRM3KCNN4 | |
| SCHEMBL4740203 | 0.80 | CHRM3 (0.77) | CHRM3OPRM1 | |
| SCHEMBL2126812 | 0.80 | CHRM3 (0.62) | CHRM3KCNN4SRC | |
| SCHEMBL2128020 | 0.80 | SMN1; SMN2 (0.52) | CHRM3KCNN4OPRM1 | |
| SCHEMBL4736843 | 0.79 | CHRM3 (0.66) | CHRM3KCNN4 | |
| SCHEMBL14162123 | 0.79 | CHRM3 (1.00) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075006-A1 | PIPERLDINUM COMPOUNDS FOR TREATMENT OF OBSTRUCTIVE PULMONARY DISEASES ( COPD) | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008075006-A1 | PIPERLDINUM COMPOUNDS FOR TREATMENT OF OBSTRUCTIVE PULMONARY DISEASES ( COPD) | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |