Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896128 | 0.89 | CETP (0.59) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL17387585 | 0.88 | PTGDR2 (0.40) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL1922337 | 0.86 | GPBAR1 (0.45) | CETPGPBAR1TBXA2RPTGDRPTGDR2 | |
| SCHEMBL1921901 | 0.82 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL154820 | 0.81 | PTGDR2 (0.45) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL153236 | 0.81 | HDAC1 (0.41) | CETPGPBAR1TBXA2RPTGDRPTGDR2 | |
| SCHEMBL1896131 | 0.80 | TACR1 (0.39) | CETPTACR1 | |
| SCHEMBL3557843 | 0.80 | CETP (0.50) | CETPGPBAR1TACR1 | |
| SCHEMBL13428453 | 0.79 | PTGDR2 (0.45) | CETPGPBAR1TBXA2RPTGDRPTGDR2 | |
| SCHEMBL151745 | 0.78 | PTGDR2 (0.39) | CETPTBXA2RPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951053-A2 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007047591-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-04-26 | — | — | WO | disclosed |