SCHEMBL4849439

SCHEMBL4849439

NC[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.47
SLC28A2 O43868 1/20 0.47
SLC29A1 Q99808 1/20 0.47
SLC28A3 Q9HAS3 1/20 0.47
P2RY14 Q15391 3/20 0.39
PYGB P11216 1/20 0.35
P2RY2 P41231 5/20 0.35
P2RY6 Q15077 7/20 0.35
P2RY4 P51582 2/20 0.34
CRBN Q96SW2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18660236 0.90 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL1532519 0.90 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL8941498 0.90 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL28250490 0.89 SLC28A1 (0.48) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4064968 0.88 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL28236932 0.88 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL7611046 0.88 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL121731 0.88 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL9644061 0.88 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL6389231 0.88 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119375375-A Method for detecting nucleotide, cap analogue and nucleic acid in vitro transcription product 楷拓生物科技(苏州)有限公司 2025-01-28 CN disclosed
US-20200038429-A1 P-ETHOXY NUCLEIC ACIDS FOR IGF-1R INHIBITION Bio-Path Holdings, Inc. (US) 2020-02-06 US disclosed
US-10335428-B2 P-ethoxy nucleic acids for liposomal formulation Bio-Path Holdings, Inc. (US) 2019-07-02 US disclosed
CN-108472354-A Respiratory syncytial virus vaccines 摩登纳特斯有限公司 2018-08-31 CN disclosed
US-20180161360-A1 P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION Bio-Path Holdings, Inc. (US) 2018-06-14 US disclosed
CN-102575252-B For polynucleotide, the compoistion and method of use of multivalence RNA interference HALO-BIO RNAI THERAPEUTICS, INC. (US) 2016-04-20 CN disclosed
CN-104830812-A Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities ATYR PHARMA INC 2015-08-12 CN disclosed
US-8592384-B2 Micro-RNA's that regulate muscle cells THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-11-26 US disclosed
CN-102575252-A Polynucleotides for multivalent RNA interference, compositions and methods of use thereof HALO BIO RNAI THERAPEUTICS INC 2012-07-11 CN disclosed
US-7452705-B2 N4 virion single-stranded DNA dependent RNA polymerase THE UNIVERSITY OF CHICAGO (US) 2008-11-18 US disclosed
US-20060246491-A1 Micro-RNA's that regulate muscle cells THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2006-11-02 US disclosed
EP-0828856-B1 NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES BIO RAD LABORATORIES (US) 2005-12-21 EP disclosed
EP-0828856-A4 NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES BIO RAD LABORATORIES (US) 2001-11-21 EP disclosed
US-5843650-A Nucleic acid detection and amplification by chemical linkage of oligonucleotides SEGEV DAVID (IL) 1998-12-01 US disclosed
EP-0828856-A1 NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES BIO-RAD LABORATORIES, INC. (US) 1998-03-18 EP disclosed
WO-1996034984-A1 NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES BIO-RAD LABORATORIES INC. (US) 1996-11-07 WO disclosed