Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.69 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.69 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.69 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.69 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.67 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.65 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.65 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660235 | 0.91 | SLC28A1 (0.66) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL12988228 | 0.89 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL1532521 | 0.89 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4064962 | 0.89 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL7611038 | 0.88 | P2RY14 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL121732 | 0.88 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL12259056 | 0.88 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4950157 | 0.88 | SLC28A1 (0.72) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4741075 | 0.88 | SLC28A1 (0.72) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL5612643 | 0.87 | SLC28A1 (0.71) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038429-A1 | P-ETHOXY NUCLEIC ACIDS FOR IGF-1R INHIBITION | Bio-Path Holdings, Inc. (US) | 2020-02-06 | — | — | US | disclosed |
| US-10335428-B2 | P-ethoxy nucleic acids for liposomal formulation | Bio-Path Holdings, Inc. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180161360-A1 | P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION | Bio-Path Holdings, Inc. (US) | 2018-06-14 | — | — | US | disclosed |
| CN-102575252-B | For polynucleotide, the compoistion and method of use of multivalence RNA interference | HALO-BIO RNAI THERAPEUTICS, INC. (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-104830812-A | Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities | ATYR PHARMA INC | 2015-08-12 | — | — | CN | disclosed |
| US-8592384-B2 | Micro-RNA's that regulate muscle cells | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-11-26 | — | — | US | disclosed |
| CN-102575252-A | Polynucleotides for multivalent RNA interference, compositions and methods of use thereof | HALO BIO RNAI THERAPEUTICS INC | 2012-07-11 | — | — | CN | disclosed |
| US-7452705-B2 | N4 virion single-stranded DNA dependent RNA polymerase | THE UNIVERSITY OF CHICAGO (US) | 2008-11-18 | — | — | US | disclosed |
| US-20060246491-A1 | Micro-RNA's that regulate muscle cells | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2006-11-02 | — | — | US | disclosed |
| EP-0828856-B1 | NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES | BIO RAD LABORATORIES (US) | 2005-12-21 | — | — | EP | disclosed |
| EP-0828856-A4 | NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES | BIO RAD LABORATORIES (US) | 2001-11-21 | — | — | EP | disclosed |
| US-5843650-A | Nucleic acid detection and amplification by chemical linkage of oligonucleotides | SEGEV DAVID (IL) | 1998-12-01 | — | — | US | disclosed |
| EP-0828856-A1 | NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES | BIO-RAD LABORATORIES, INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996034984-A1 | NUCLEIC ACID DETECTION AND AMPLIFICATION BY CHEMICAL LINKAGE OF OLIGONUCLEOTIDES | BIO-RAD LABORATORIES INC. (US) | 1996-11-07 | — | — | WO | disclosed |