Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808174 | 0.89 | OPRL1 (0.54) | OPRL1CHRM4TACR1OPRM1KCNH2 | |
| SCHEMBL4848475 | 0.84 | SLC6A4 (0.47) | OPRL1CHRM4TACR1OPRM1SLC6A4 | |
| SCHEMBL4855793 | 0.84 | OPRL1 (0.53) | OPRL1CHRM4TACR1OPRM1KCNH2 | |
| SCHEMBL4849548 | 0.82 | OPRL1 (0.51) | OPRL1CHRM4TACR1OPRM1SLC6A4 | |
| SCHEMBL4848259 | 0.81 | SLC6A4 (0.52) | OPRL1TACR1OPRM1SLC6A4SLC6A2 | |
| SCHEMBL4852940 | 0.81 | TACR1 (0.46) | TACR1SLC6A4SLC6A2SLC6A3KDM4E | |
| SCHEMBL2834684 | 0.79 | OPRL1 (0.54) | OPRL1CHRM4TACR1OPRM1SLC6A4 | |
| SCHEMBL17606613 | 0.79 | OPRL1 (0.48) | OPRL1OPRM1SLC6A4ALDH1A1USP2 | |
| SCHEMBL699951 | 0.79 | OPRL1 (0.63) | OPRL1CHRM4TACR1OPRM1SLC6A4 | |
| SCHEMBL2808157 | 0.77 | OPRL1 (0.56) | OPRL1CHRM4OPRM1KCNH2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423039-B2 | (4-phenylpiperazin-1-yl)acylpiperidine derivatives, preparation thereof and application of same in therapeutics | SANOFI-AVENTIS (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20070021609-A1 | 4-PHENYLPIPERAZIN-1-YL)ACYLPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021609-A1 | 4-PHENYLPIPERAZIN-1-YL)ACYLPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | AGPAT5, DNPEP, AGPAT2 | OPRL1 2532/4885CHRM4 2925/4885TACR1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.