Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310841 | 0.86 | TYRO3 (0.50) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| SCHEMBL29480586 | 0.86 | PRKD3 (0.49) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| SCHEMBL340944 | 0.86 | PRKD3 (0.49) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| SCHEMBL29388621 | 0.86 | TYRO3 (0.50) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL29487293 | 0.84 | TYRO3 (0.48) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL30594385 | 0.84 | PRKD3 (0.47) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL30775701 | 0.84 | PRKD3 (0.47) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| SCHEMBL2121736 | 0.80 | PRKD3 (0.44) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| Biphenyl SCHEMBL28782742 | 0.78 | GSK3A (0.63) | PDE3BPDE3APIM1PRKD3MAP4K4 | |
| SCHEMBL360425 | 0.71 | PARP1 (0.55) | PDE3BPDE3AAURKAPARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075007-A1 | MORPHOLINO-SUBSTITUTED BICYCLOHETEROARYL COMPOUNDS AND THEIR USE AS ANTI CANCER AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |