SCHEMBL4850233

SCHEMBL4850233

C=CC(=O)OCC(O)CBr

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 5/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 3/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 2/20 0.39
MAPK1 P28482 1/20 0.39
THRB P10828 2/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20340335 1.00 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
Dimethylamine SCHEMBL1302761 0.93 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
Trimethylammonium SCHEMBL1302157 0.93 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1302161 0.89 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
Diethylamine SCHEMBL1302461 0.88 TSHR (0.49) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL95157 0.87 TSHR (0.64) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4845895 0.84 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4843885 0.83 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL203723 0.81 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL115220 0.81 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4264705-A Multilayered elastomeric printing plate UNIROYAL, INC. (US) 1981-04-28 US claimed
US-4192684-A Photosensitive compositions containing hydrogenated 1,2-polybutadiene ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-03-11 US claimed
CN-120036308-A Deodorizing and disinfecting spray composition and preparation method and application thereof 奥洁玛(北京)生物科技有限公司 2025-05-27 CN disclosed
US-11152413-B2 Structure, method for producing structure, composition for forming absorption layer, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2021-10-19 US disclosed
US-20200119071-A1 STRUCTURE, METHOD FOR PRODUCING STRUCTURE, COMPOSITION FOR FORMING ABSORPTION LAYER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-04-16 US disclosed
US-7459185-B2 Treatment of natural polymer based materials and the products based thereon COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2008-12-02 US disclosed
US-20050048207-A1 Treatment of natural polymer based materials and the products based thereon COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-03-03 US disclosed
US-6830784-B2 Treating natural polymeric material with a modifying agent selected from coupling agents and multi-functional amine compounds; subjecting to solvent extraction and/or treatment with physical field and/or oxidation COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-12-14 US disclosed
US-6800331-B2 REACTING THE FUNCTIONALIZED SURFACE WITH A COMPOUND CONTAININGAT LEAST FOUR AMINE GROUPS AND A CROSSLINKING AGENT REACTIVE WITH THE POLYAMINE; TO PROVIDE A CROSSLINKED NETWORK GRAFTED TO THE SUBSTRATE SURFACE. COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-10-05 US disclosed
EP-1242516-B1 PREPARATION OF FUNCTIONAL POLYMERIC SURFACE COMMW SCIENT IND RES ORG (AU) 2004-08-25 EP disclosed
EP-1253999-A4 TREATMENT OF NATURAL POLYMER BASED MATERIALS AND THE PRODUCTS BASED THEREON COMMW SCIENT IND RES ORG (AU) 2004-08-11 EP disclosed
US-4264705-A Multilayered elastomeric printing plate UNIROYAL, INC. (US) 1981-04-28 US disclosed
US-4192684-A Photosensitive compositions containing hydrogenated 1,2-polybutadiene ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-03-11 US disclosed
US-4187366-A Amide-modified urethane acrylate radiation curable compounds derived from condensation reaction products of carboxyl and isocyanato groups PPG INDUSTRIES, INC. (US) 1980-02-05 US disclosed
US-4153776-A Amide-modified urethane acrylate radiation curable compounds and coating compositions and methods of making same PPG INDUSTRIES, INC. (US) 1979-05-08 US disclosed
US-4108840-A Urea-urethane-acrylate radiation curable coating compositions and methods of making same PPG INDUSTRIES, INC. (US) 1978-08-22 US disclosed
US-4091050-A Method for the preparation of mixtures of (meth)acrylic terminated polyether resin and 3-halo-2-hydroxypropyl (meth)acrylate PPG INDUSTRIES, INC. (US) 1978-05-23 US disclosed
US-4065624-A Radiation curable coating composition PPG INDUSTRIES, INC. (US) 1977-12-27 US disclosed
US-4006024-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-02-01 US disclosed
US-3960572-A Photosensitive compositions comprising a polyester-polyether block polymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-06-01 US disclosed