Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL4264567 | 0.90 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL4612528 | 0.90 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL28670127 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL20490104 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL29078554 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL29615874 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL28910121 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL899292 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Isopropyl Alcohol SCHEMBL17433507 | 0.86 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| Acetic Acid SCHEMBL7442100 | 0.86 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230120549-A1 | Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same | PPG INDUSTRIES OHIO, INC. | 2023-04-20 | — | — | US | disclosed |
| US-20220119581-A1 | Aircraft Windows | PPG INDUSTRIES, INC. | 2022-04-21 | — | — | US | disclosed |
| US-11248083-B2 | Aircraft windows | PPG INDUSTRIES OHIO, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| US-20200165375-A1 | \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ | PPG INDUSTRIES OHIO, INC. | 2020-05-28 | — | — | US | disclosed |
| US-10590230-B2 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-20200071451-A1 | Aircraft Windows | PPG INDUSTRIES, INC. | 2020-03-05 | — | — | US | disclosed |
| US-20180282470-A1 | Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same | PPG INDUSTRIES OHIO, INC. | 2018-10-04 | — | — | US | disclosed |
| US-9951173-B2 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20180051123-A1 | Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same | PPG INDUSTRIES OHIO, INC. | 2018-02-22 | — | — | US | disclosed |
| US-9822211-B2 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20070167600-A1 | Polyurethanes prepared from polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070155936-A1 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155942-A1 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155895-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155935-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070149749-A1 | Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070149748-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070148471-A1 | Impact resistant polyurethane and poly(ureaurethane) articles and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070149747-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| WO-2007070627-A2 | POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME | PPG INDUSTRIES OHIO, INC. (US) | 2007-06-21 | — | — | WO | disclosed |