Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852578 | 1.00 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1CRHBPCRHR2 | |
| SCHEMBL4856844 | 0.89 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4845951 | 0.89 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL4845948 | 0.89 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL4856854 | 0.89 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4853490 | 0.88 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4853481 | 0.88 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4855188 | 0.88 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4855193 | 0.88 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4848464 | 0.88 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724275-B1 | PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE | JAPAN SCIENCE & TECH AGENCY (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-7375244-B2 | Production method for aminophosphonic acid derivatives | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-05-20 | — | — | US | disclosed |
| EP-1724275-A1 | PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE | Japan Science and Technology Agency (JP) | 2006-11-22 | — | — | EP | disclosed |