Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.58 |
| ▸ | CNR2 | P34972 | 6/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847654 | 0.85 | HRH1 (0.57) | HRH1CYP2D6KCNH2CNR2CNR1 | |
| SCHEMBL4848844 | 0.80 | HRH1 (0.54) | HRH1CYP2D6KCNH2CNR2CNR1 | |
| SCHEMBL4848815 | 0.79 | HRH1 (0.57) | HRH1CYP2D6KCNH2CHRM1CYP3A4 | |
| SCHEMBL4851119 | 0.77 | CNR2 (0.56) | HRH1CYP2D6KCNH2CNR2CNR1 | |
| SCHEMBL4847028 | 0.76 | HRH1 (0.58) | HRH1CYP2D6KCNH2CNR2CNR1 | |
| SCHEMBL6072831 | 0.75 | HRH1 (0.61) | HRH1CYP2D6KCNH2CHRM1CYP3A4 | |
| SCHEMBL14107009 | 0.74 | HRH1 (0.57) | HRH1CYP2D6KCNH2CNR2CNR1 | |
| SCHEMBL4850652 | 0.74 | HRH1 (0.57) | HRH1CYP2D6KCNH2CHRM1CYP3A4 | |
| SCHEMBL4848857 | 0.74 | HRH1 (0.50) | HRH1CYP2D6KCNH2CNR2CNR1 | |
| SCHEMBL4850526 | 0.74 | HRH1 (0.55) | HRH1CYP2D6KCNH2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393865-B2 | Sleep inducing compounds and methods relating thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-07-01 | — | — | US | disclosed |