Dl-Tryptophan

Dl-Tryptophan

SCHEMBL4852909

CC(C)C(N)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.82
MAPT P10636 3/20 0.82
KMT2A Q03164 3/20 0.82
LMNA P02545 2/20 0.82
TSHR P16473 2/20 0.82
BLM P54132 2/20 0.82
PMP22 Q01453 2/20 0.82
MEN1 O00255 2/20 0.82
MPO P05164 1/20 0.82
HIF1A Q16665 1/20 0.82
APAF1 O14727 1/20 0.65
POLB P06746 1/20 0.65
RECQL P46063 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
CTSC P53634 1/20 0.60
HTR2A P28223 3/20 0.59
HTR1A P08908 2/20 0.59
HTR2C P28335 2/20 0.59
SLC6A4 P31645 2/20 0.59
HTR7 P34969 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL11880165 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL10527499 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL8814131 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL4852913 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL10527472 0.99 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL3497630 0.97 KDM4E (0.78) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL7154073 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL22091568 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL7859113 0.95 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL20504023 0.93 KDM4E (0.71) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314269-A1 3-METHYLCROTONIC ACID DECARBOXYLASE (MDC) VARIANTS Global Bioenergies (FR) 2024-02-07 EP claimed
WO-2022207684-A1 3-METHYLCROTONIC ACID DECARBOXYLASE (MDC) VARIANTS GLOBAL BIOENERGIES (FR) 2022-10-06 WO claimed
WO-2017068548-A1 NOVEL AMINO ACID/PEPTIDE-ZINC HYBRID NANOMATERIALS AND PROCESS OF PREPARATION THEREOF BHANAGE BHALCHANDRA MAHADEO (IN) 2017-04-27 WO claimed
EP-4384607-A1 ENZYMATIC DEGRADATION OF POLYETHYLENE TEREPHTHALATE Biometis Technology, Inc. (US) 2024-06-19 EP disclosed
EP-4314269-A1 3-METHYLCROTONIC ACID DECARBOXYLASE (MDC) VARIANTS Global Bioenergies (FR) 2024-02-07 EP disclosed
CN-108852925-B Composition containing aqueous extract of dill rich in small RNA and its use in cosmetics ISP 投资有限责任公司 2023-03-17 CN disclosed
WO-2023019222-A1 ENZYMATIC DEGRADATION OF POLYETHYLENE TEREPHTHALATE BIOMETIS TECHNOLOGY, INC. (US) 2023-02-16 WO disclosed
WO-2022207684-A1 3-METHYLCROTONIC ACID DECARBOXYLASE (MDC) VARIANTS GLOBAL BIOENERGIES (FR) 2022-10-06 WO disclosed
US-20220154109-A1 Mutant Protease KAO CORPORATION (JP) 2022-05-19 US disclosed
CN-108603181-B Phytase and use thereof 福尼亚生物处理股份有限公司 2022-03-08 CN disclosed
CN-114126570-A Oral care compositions for active agent delivery 宝洁公司 2022-03-01 CN disclosed
WO-2003101436-A1 NOVEL CHROMIUM (III) ALPHA AMINO ACID COMPLEXES ZINPRO CORPORATION (US) 2003-12-11 WO disclosed
EP-0951532-A4 BIVALENT AGONISTS FOR G-PROTEIN COUPLED RECEPTORS UNIV YALE (US) 2000-08-30 EP disclosed
EP-0951532-A1 BIVALENT AGONISTS FOR G-PROTEIN COUPLED RECEPTORS YALE UNIVERSITY (US) 1999-10-27 EP disclosed
EP-0877811-A1 MUTATED PRENYL DIPHOSPHATE SYNTHASES Toyota Jidosha Kabushiki Kaisha (JP) 1998-11-18 EP disclosed
WO-1998020138-A1 MUTATED PRENYL DIPHOSPHATE SYNTHASES TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1998-05-14 WO disclosed
WO-1998003632-A1 BIVALENT AGONISTS FOR G-PROTEIN COUPLED RECEPTORS YALE UNIVERSITY (US) 1998-01-29 WO disclosed
EP-0561866-A1 LYOPHILIZED AMINO ACID COMPOSITIONS CONTAINING GLUTAMINE. TORRE A FARMACEUTICI (IT) 1993-09-29 EP disclosed
WO-1992010175-A1 LYOPHILIZED AMINO ACID COMPOSITIONS CONTAINING GLUTAMINE DR. A. TORRE FARMACEUTICI S.R.L. (IT) 1992-06-25 WO disclosed
EP-0491014-A1 Sm-D ANTIGEN PEPTIDES AND THEIR USE, IN PARTICULAR, FOR THE DIAGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS. NEOSYSTEM SA (FR) 1992-06-24 EP disclosed