SCHEMBL4853402

SCHEMBL4853402

CCSc1ccccc1C(=O)O.CCSc1ccccc1C(=O)O.[Hg].[NaH]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.62
RAB9A P51151 4/20 0.57
POLB P06746 4/20 0.57
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA4 P22748 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
NPC1 O15118 3/20 0.54
HSP90AA1 P07900 1/20 0.54
ALDH1A1 P00352 3/20 0.52
GAA P10253 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PTPRG P23470 1/20 0.49
HSD17B10 Q99714 4/20 0.48
HPGD P15428 4/20 0.48
MAPK1 P28482 3/20 0.48
LMNA P02545 2/20 0.48
TSHR P16473 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728287 0.98 CYP1A2 (0.65) CYP1A2RAB9APOLBCA12CA1
SCHEMBL2747847 0.96 CYP1A2 (0.67) CYP1A2RAB9APOLBCA12CA1
SCHEMBL27998062 0.94 CYP1A2 (0.65) CYP1A2RAB9APOLBCA12CA1
Hydrochloric Acid SCHEMBL9952241 0.94 CYP1A2 (0.65) CYP1A2RAB9APOLBCA12CA1
SCHEMBL6779779 0.81 CYP1A2 (0.62) CYP1A2RAB9APOLBCA12CA1
SCHEMBL4436794 0.81 HSD17B10 (0.54) CYP1A2POLBCA12CA1CA2
SCHEMBL6230251 0.80 CYP1A2 (0.71) CYP1A2RAB9APOLBCA12CA1
SCHEMBL6231914 0.80 CYP1A2 (0.71) CYP1A2RAB9APOLBCA12CA1
SCHEMBL1830472 0.80 POLB (0.49) CYP1A2RAB9APOLBCA12CA1
SCHEMBL9755026 0.80 HPGD (0.52) CYP1A2RAB9APOLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1230523-A None JP disclosed
US-7344852-B1 Crystallization of dipeptidyl peptidase IV (DPPIV) TAKEDA SAN DIEGO, INC. (US) 2008-03-18 US disclosed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP disclosed
CN-1019133-B MONOCLONAL ANTIBODIES TO PSEUDOMONAS AERUGINOSA FLAGELLA GENETIC SYSTEMS CORP (US) 1992-11-18 CN disclosed
CN-1009963-B RUTHENIUM COMPLEX BEING ABLE COUPLED WITH IMMUNO-ACTIVITY MATERIALS HOFFMANN LA ROCHE (CH) 1990-10-10 CN disclosed
JP-H01230523-A INACTIVATED VACCINE AND ITS PREPARATION BEECHAM INC 1989-09-14 JP disclosed
CN-87104581-A The monoclonal antibody of resisting pseudomonas aeruginosa flagellum 1988-09-21 CN disclosed
CN-86106632-A Acquired Immunodeficiency Syndrome (AIDS) Vaccine 1987-05-13 CN disclosed
CN-85107032-A The preparation of ruthenium complex and application 1987-04-01 CN disclosed
CN-86104525-A The analytical approach of human interleukin-2 and reagent 1987-02-25 CN disclosed
CN-85107805-A Manufacture method as N-alkenyl-3-hydroxy benzo [b] the thiophene-2-carboxamide derivatives derivative of dual-purpose cyclooxygenase and lipoxidase inhibitor 1986-12-31 CN disclosed