Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.64 |
| ▸ | CTSD | P07339 | 9/20 | 0.61 |
| ▸ | BACE2 | Q9Y5Z0 | 9/20 | 0.61 |
| ▸ | REN | P00797 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533029 | 0.83 | BACE1 (0.66) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL3541368 | 0.83 | BACE1 (0.66) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL3534104 | 0.83 | BACE1 (0.66) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL8197520 | 0.82 | BACE1 (0.61) | BACE1CTSDBACE2RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL4914674 | 0.82 | BACE1 (0.60) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL2796254 | 0.79 | BACE1 (0.83) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL8194024 | 0.79 | BACE1 (0.74) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL2794328 | 0.79 | BACE1 (0.74) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL2795477 | 0.79 | BACE1 (0.90) | BACE1CTSDBACE2RENCYP3A4 | |
| SCHEMBL2792706 | 0.79 | BACE1 (0.73) | BACE1CTSDBACE2RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |