Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32666117 | 0.79 | TSHR (0.56) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL19487102 | 0.78 | TSHR (0.54) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL14031946 | 0.77 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL15911114 | 0.76 | TSHR (0.53) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL32666115 | 0.75 | TSHR (0.51) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL32666111 | 0.75 | ASAH1 (0.60) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13248693 | 0.75 | TSHR (0.51) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL3810000 | 0.75 | ASAH1 (0.60) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL12617848 | 0.75 | TSHR (0.46) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL15889162 | 0.74 | ASAH1 (0.44) | TSHRALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368586-B2 | Organosilicon compounds with a masked isocyanate group | WACKER CHEMIE AG (DE) | 2008-05-06 | — | — | US | disclosed |
| EP-1771457-B1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | WACKER CHEMIE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| US-20070123644-A1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | WACKER CHEMIE AG (DE) | 2007-05-31 | — | — | US | disclosed |