Sugi Predict

Sugi Predict / Compounds / SCHEMBL485372

SCHEMBL485372

SCHEMBL485372

CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C(On1nnc2ccccc21)=[N+](C)C.[O-]B([O-])F.[O-]B([O-])F.[O-]B([O-])F.[O-]B([O-])F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 4/20 0.43
▸ HDAC3 O15379 3/20 0.43
▸ HDAC4 P56524 3/20 0.43
▸ HDAC1 Q13547 3/20 0.43
▸ HDAC7 Q8WUI4 3/20 0.43
▸ HDAC2 Q92769 3/20 0.43
▸ HDAC10 Q969S8 3/20 0.43
▸ HDAC11 Q96DB2 3/20 0.43
▸ HDAC8 Q9BY41 3/20 0.43
▸ HDAC6 Q9UBN7 3/20 0.43
▸ HDAC9 Q9UKV0 3/20 0.43
▸ HDAC5 Q9UQL6 3/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.39
▸ TSHR P16473 1/20 0.39
▸ RXFP1 Q9HBX9 1/20 0.39
▸ KMT2A Q03164 4/20 0.37
▸ MAPT P10636 2/20 0.37
▸ SIRT1 Q96EB6 1/20 0.36
▸ SIRT3 Q9NTG7 1/20 0.36
▸ DGAT1 O75907 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16765691 1.00 SIRT2 (0.43) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL5794054 1.00 SIRT2 (0.43) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL1941414 1.00 SIRT2 (0.43) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL3771508 0.95 SIRT2 (0.45) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL16765695 0.95 SIRT2 (0.45) SIRT2HDAC3HDAC4HDAC1HDAC7
Fluoride Ion SCHEMBL28343186 0.94 SIRT2 (0.44) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL5332210 0.94 SIRT2 (0.44) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL29544944 0.92 SIRT2 (0.49) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL118552 0.92 SIRT2 (0.49) SIRT2HDAC3HDAC4HDAC1HDAC7
Fluoride Ion SCHEMBL4594160 0.91 SIRT2 (0.48) SIRT2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379484-B1 POLYUNSATURATED FATTY ACID AND DIOL ESTER AS AN ANTI-ACNE AGENT FABRE PIERRE DERMO COSMETIQUE (FR) 2013-05-29 — — EP claimed
EP-0929567-B1 SOLID-PHASE PEPTIDE SYNTHESIS ZEALAND PHARMA AS (DK) 2005-03-02 — — EP claimed
EP-0948523-B1 PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE BOEHRINGER INGELHEIM CA LTD (CA) 2004-03-17 — — EP claimed
EP-3487856-B1 SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE BAYER AG (DE) 2025-01-22 — — EP disclosed
EP-3638675-B1 DIAZABICYCLIC SUBSTITUTED IMIDAZOPYRIMIDINES AND THEIR USE FOR THE TREATMENT OF BREATHING DISORDERS BAYER AG (DE) 2024-04-17 — — EP disclosed
US-20230355638-A1 Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists BOEHRINGER INGELHEIM INT (DE) 2023-11-09 — — US disclosed
EP-4244229-A1 CYCLOPENTATHIOPHENE CARBOXAMIDE DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS Boehringer Ingelheim International GmbH (DE) 2023-09-20 — — EP disclosed
US-11591367-B2 Melanocortin-1-receptor agonists DSM IP ASSETS B.V. (NL) 2023-02-28 — — US disclosed
WO-2022101377-A1 CYCLOPENTATHIOPHENE CARBOXAMIDE DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-05-19 — — WO disclosed
EP-3704134-B1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS BV (NL) 2021-12-22 — — EP disclosed
EP-3523316-B1 MELANOCORTIN-1-RECEPTOR AGONISTS DSM IP ASSETS BV (NL) 2021-11-03 — — EP disclosed
EP-0649426-A1 INHIBITORS OF RETROVIRAL PROTEASES HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-26 — — EP disclosed
EP-0497915-B1 hPTH (1-37) FRAGMENT, ITS PRODUCTION, DRUG CONTAINING IT AND ITS USE HAEMOPEP PHARMA GMBH (DE) 1995-04-19 — — EP disclosed
WO-1994024153-A1 CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION CIBA-GEIGY AG (CH) 1994-10-27 — — WO disclosed
EP-0592949-A2 N-(aminocarbonyl)-piperidines/pepirazines as aggregation inhibiting agents Dr. Karl Thomae GmbH (DE) 1994-04-20 — — EP disclosed
EP-0410278-B1 Renin inhibiting aminooligohydroxy-derivatives HOECHST AG (DE) 1994-01-19 — — EP disclosed
WO-1994000461-A1 INHIBITORS OF RETROVIRAL PROTEASES HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-06 — — WO disclosed
EP-0435059-A1 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-03 — — EP disclosed
EP-0428849-A2 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-29 — — EP disclosed
EP-0410278-A1 Renin inhibiting aminooligohydroxy-derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591367-B2 Melanocortin-1-receptor agonists MC1R, MC3R, MC5R SIRT2 1584/4885HDAC3 1168/4885HDAC4 2195/4885
US-20230355638-A1 Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists PTAFR, PDGFRA, F3 SIRT2 2262/4885HDAC3 3674/4885HDAC4 3736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.