Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL20188174 | 1.00 | GABRR1 (0.50) | GABRR1SLC7A5CHRM1AKR1A1CHRM3 | |
| Alanine SCHEMBL22616405 | 0.88 | — | — | |
| Alanine SCHEMBL6468817 | 0.88 | SLC7A5 (0.48) | GABRR1SLC7A5CHRM1AKR1A1CHRM3 | |
| Alanine SCHEMBL4853752 | 0.88 | — | — | |
| Alanine SCHEMBL11876922 | 0.88 | SLC7A5 (0.48) | GABRR1SLC7A5CHRM1AKR1A1CHRM3 | |
| Alanine SCHEMBL20740651 | 0.88 | GABRR1 (0.55) | GABRR1SLC7A5SLC1A3SLC1A2SLC1A1 | |
| D-Alanine SCHEMBL28148207 | 0.87 | GSR (0.46) | GABRR1SLC1A3SLC1A2SLC1A1GRIK1 | |
| Alanine SCHEMBL27624409 | 0.87 | GSR (0.46) | GABRR1SLC1A3SLC1A2SLC1A1GRIK1 | |
| Alanine SCHEMBL28824467 | 0.86 | SLC7A5 (0.46) | GABRR1SLC7A5CHRM1AKR1A1CHRM3 | |
| Alanine SCHEMBL28824465 | 0.86 | SLC7A5 (0.46) | GABRR1SLC7A5CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928504-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014093394-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2014-06-19 | — | — | WO | disclosed |
| EP-2717916-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012171020-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| US-7452701-B2 | Methods for the preparation of β-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-11-18 | — | — | US | disclosed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | disclosed |