Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.62 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860298 | 0.87 | MAP2K1 (0.76) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4851636 | 0.83 | MAP2K1 (0.77) | MAP2K1MAP2K2 | |
| SCHEMBL4861995 | 0.81 | MAP2K1 (0.62) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4862032 | 0.81 | MAP2K1 (0.62) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4854378 | 0.80 | MAP2K1 (0.76) | MAP2K1MAP2K2 | |
| Benzamide SCHEMBL7052142 | 0.78 | MAP2K1 (0.54) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL7050814 | 0.78 | MAP2K1 (0.59) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4863510 | 0.78 | MAP2K1 (0.73) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4861807 | 0.77 | MAP2K1 (0.81) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL1341919 | 0.76 | KDM4E (0.52) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411001-B2 | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER-LAMBERT COMPANY (US) | 2008-08-12 | — | — | US | claimed |
| EP-1301472-B1 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER LAMBERT CO (US) | 2014-03-26 | — | — | EP | disclosed |