Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486027 | 0.98 | MAOB (0.50) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| Formic Acid SCHEMBL27693206 | 0.94 | MAOB (0.47) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL485800 | 0.87 | KMT2A (0.49) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL486121 | 0.85 | MAOB (0.47) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL486258 | 0.84 | MAOB (0.52) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| Formic Acid SCHEMBL28768792 | 0.83 | MAOB (0.45) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| Bicarbonate SCHEMBL485447 | 0.82 | MAOB (0.50) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL485628 | 0.81 | CXCR2 (0.58) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL484358 | 0.81 | CXCR2 (0.56) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| Formic Acid SCHEMBL27693254 | 0.81 | MAOB (0.48) | MAOBALDH1A1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836158-B1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES FOR USE AS CXCR2 INHIBITORS IN THE TREATMENT OF INFLAMMATION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-02-01 | — | — | EP | claimed |