⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12186604 | 0.80 | GAA (0.43) | — | |
| SCHEMBL1650868 | 0.78 | EGLN3 (0.40) | — | |
| Bromide SCHEMBL8403330 | 0.76 | GAA (0.39) | — | |
| SCHEMBL8708390 | 0.76 | GAA (0.40) | — | |
| SCHEMBL21217536 | 0.70 | GAA (0.41) | — | |
| SCHEMBL7810279 | 0.69 | GAA (0.37) | — | |
| SCHEMBL10516246 | 0.67 | GAA (0.36) | — | |
| SCHEMBL23256274 | 0.67 | GAA (0.38) | — | |
| SCHEMBL5657617 | 0.66 | CYP19A1 (0.48) | — | |
| SCHEMBL31249951 | 0.66 | GAA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517906-B1 | METHOD FOR THE PRODUCTION OF 1,2,4-TRIAZOLYLMETHYL-OXIRANES | BASF AG (DE) | 2007-03-28 | — | — | EP | claimed |
| US-20050176967-A1 | Preparation for the production of 1,2,4-triazolymethyl-oxiranes | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | claimed |
| US-7368464-B2 | Preparation for the production of 1,2,4-triazolylmethyl-oxiranes | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-06 | — | — | US | disclosed |
| US-7368464-B2 | Preparation for the production of 1,2,4-triazolylmethyl-oxiranes | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-06 | — | — | US | disclosed |
| CN-100345841-C | Preparation for the production of 1,2,4-triazolymethyl-oxiranes | BASF AG (DE) | 2007-10-31 | — | — | CN | disclosed |
| EP-1517906-B1 | METHOD FOR THE PRODUCTION OF 1,2,4-TRIAZOLYLMETHYL-OXIRANES | BASF AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| CN-1662525-A | Preparation for the production of 1,2,4-triazolymethyl-oxiranes | BASF AG (DE) | 2005-08-31 | — | — | CN | disclosed |
| US-20050176967-A1 | Preparation for the production of 1,2,4-triazolymethyl-oxiranes | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | disclosed |
| US-20050176967-A1 | Preparation for the production of 1,2,4-triazolymethyl-oxiranes | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | disclosed |
| EP-1517906-A1 | METHOD FOR THE PRODUCTION OF 1,2,4-TRIAZOLYLMETHYL-OXIRANES | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000835-A1 | METHOD FOR THE PRODUCTION OF 1,2,4-TRIAZOLYLMETHYL-OXIRANES | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-31 | — | — | WO | disclosed |
| EP-0321131-A2 | Triazole antifungal agents | Pfizer Limited (GB) | 1989-06-21 | — | — | EP | disclosed |
| EP-0258785-A2 | Substituted mercapto-hydroxyethyl-(triazol-1-yl) derivatives | BAYER AG (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258782-A2 | Use of 1-(substituted mercapto-hydroxyethyl)-triazoles in the treatment of illnesses | BAYER AG (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0084834-A2 | Substituted 1-hydroxyalkyl-azolyl-derivatives, process for their preparation and use as fungicides and plant-growth regulation | BAYER AG (DE) | 1983-08-03 | — | — | EP | disclosed |