Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856814 | 1.00 | KDM4E (0.44) | KDM4ECA2PTGS1MMP12NFKB1 | |
| SCHEMBL1956799 | 1.00 | KDM4E (0.44) | KDM4ECA2PTGS1MMP12NFKB1 | |
| SCHEMBL20754653 | 0.87 | — | — | |
| SCHEMBL1358143 | 0.83 | — | — | |
| SCHEMBL1358140 | 0.83 | — | — | |
| SCHEMBL6194847 | 0.83 | — | — | |
| SCHEMBL3858865 | 0.81 | — | — | |
| SCHEMBL11093870 | 0.81 | — | — | |
| SCHEMBL14930918 | 0.81 | — | — | |
| SCHEMBL17753807 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687349-B1 | POLYAMINE POLYMERS | ILYPSA INC (US) | 2008-06-18 | — | — | EP | disclosed |
| EP-1687349-B1 | POLYAMINE POLYMERS | ILYPSA INC (US) | 2008-06-18 | — | — | EP | disclosed |
| US-7385012-B2 | Polyamine polymers | ILYPSA, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| US-7385012-B2 | Polyamine polymers | ILYPSA, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| US-7385012-B2 | Polyamine polymers | ILYPSA, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| US-7342083-B2 | Polyamine polymers | ILYPSA, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342083-B2 | Polyamine polymers | ILYPSA, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342083-B2 | Polyamine polymers | ILYPSA, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| EP-1687349-A4 | POLYAMINE POLYMERS | ILYPSA INC (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-1687349-A2 | POLYAMINE POLYMERS | Ilypsa, Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20050165190-A1 | Polyamine polymers | SYMYX THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | US | disclosed |
| WO-2005041900-A2 | POLYAMINE POLYMERS | ILYPSA, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20050096438-A1 | Polyamine polymers | SYMYX THERAPEUTICS, INC. (US) | 2005-05-05 | — | — | US | disclosed |
| WO-2000029385-A1 | 1,4,5,6-TETRAHYDRO-PYRIDAZINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS NEURAMINIDASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2000-05-25 | — | — | WO | disclosed |