Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562350 | 0.83 | KMT2A (0.38) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL346078 | 0.80 | KMT2A (0.44) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL9171084 | 0.77 | KMT2A (0.45) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL1251666 | 0.76 | KMT2A (0.44) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL28755697 | 0.75 | FABP5 (0.45) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30179376 | 0.72 | MDM4 (0.46) | KMT2AFABP5FABP7EPHX2MDM4 | |
| SCHEMBL3195566 | 0.72 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL1250338 | 0.72 | FABP5 (0.47) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL1157567 | 0.72 | FABP5 (0.49) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30662743 | 0.72 | FABP5 (0.49) | KMT2AFABP5FABP7EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402385-B2 | Radiolabeled antibodies for treatment of tumors | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2008-07-22 | — | — | US | disclosed |
| US-20060039858-A1 | Radiolabeled antibodies and peptides for treatment of tumors | NATIONAL INSTITUTES OF HEALTH | 2006-02-23 | — | — | US | disclosed |
| US-20040156780-A1 | Radiolabeled antibodies for treatment of tumors | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2004-08-12 | — | — | US | disclosed |