Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 8/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 6/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485988 | 0.85 | F2R (0.72) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL664244 | 0.84 | F2R (0.73) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10240194 | 0.81 | F2R (1.00) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10188954 | 0.73 | F2R (0.68) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10188941 | 0.71 | F2R (0.71) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL660487 | 0.71 | F2R (1.00) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL486025 | 0.71 | F2R (0.60) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL486169 | 0.71 | F2R (0.73) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10188857 | 0.71 | F2R (0.75) | F2RRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10188905 | 0.70 | F2R (0.76) | F2RRAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |