Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.62 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664273 | 0.85 | F2R (0.66) | F2RDRD4DRD2CHRM2CHRM5 | |
| SCHEMBL662583 | 0.80 | F2R (0.85) | F2RDRD4DRD2SCN1ASCN5A | |
| SCHEMBL10242081 | 0.79 | F2R (0.71) | F2RDRD4DRD2MEN1KMT2A | |
| SCHEMBL662957 | 0.79 | F2R (0.76) | F2RDRD4DRD2SCN1ASCN5A | |
| SCHEMBL486079 | 0.78 | F2R (0.69) | F2RMEN1KMT2ACHRM1 | |
| SCHEMBL661832 | 0.78 | F2R (0.64) | F2R | |
| SCHEMBL486041 | 0.78 | F2R (0.64) | F2RDRD4DRD2SCN5ASCN9A | |
| SCHEMBL10239963 | 0.76 | F2R (1.00) | F2RDRD4DRD2SCN1ASCN5A | |
| SCHEMBL661933 | 0.76 | F2R (1.00) | F2RDRD4DRD2SCN1ASCN5A | |
| SCHEMBL486313 | 0.76 | F2R (1.00) | F2RDRD4DRD2SCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |