Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.80 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242071 | 0.91 | F2R (0.80) | F2RSCN1ASCN5ASCN9AEPHX2 | |
| SCHEMBL661933 | 0.89 | F2R (1.00) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL485929 | 0.88 | F2R (0.84) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL486123 | 0.86 | F2R (0.78) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL485872 | 0.86 | F2R (0.81) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL661795 | 0.86 | F2R (0.81) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL10242089 | 0.86 | F2R (0.72) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL10242108 | 0.86 | F2R (0.91) | F2RSCN1ASCN5ASCN9ADRD2 | |
| SCHEMBL485828 | 0.86 | F2R (0.77) | F2RDRD2DRD4 | |
| SCHEMBL485965 | 0.85 | F2R (1.00) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |