⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640394 | 0.57 | — | — | |
| SCHEMBL12569206 | 0.54 | — | — | |
| SCHEMBL4861060 | 0.54 | — | — | |
| SCHEMBL6931121 | 0.54 | — | — | |
| SCHEMBL363405 | 0.53 | — | — | |
| SCHEMBL10296565 | 0.53 | — | — | |
| SCHEMBL3198705 | 0.53 | — | — | |
| SCHEMBL7591210 | 0.52 | — | — | |
| SCHEMBL3063199 | 0.49 | EGLN1 (0.42) | — | |
| SCHEMBL2379600 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492265-A1 | 1,2,4-Thiadiazole Compounds and Pests Controlling Composition Containing the same | Sumitomo Chemical Company, Limited (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-7371746-B2 | 1,2,4-Thiadiazole compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-05-13 | — | — | US | disclosed |
| EP-1765798-A2 | 1,2,4- THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| WO-2005037805-A2 | 1,2,4-THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | WO | disclosed |
| EP-1358161-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Amgen Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055501-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMGEN INC (US) | 2002-07-18 | — | — | WO | disclosed |