Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 17/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505527 | 1.00 | CACNA1B (0.51) | CACNA1BNR1I2GAAHPGDRORC | |
| SCHEMBL4855484 | 0.93 | CACNA1B (0.52) | CACNA1BNR1I2GAAHPGDRORC | |
| SCHEMBL5502128 | 0.93 | CACNA1B (0.52) | CACNA1BNR1I2GAAHPGDRORC | |
| SCHEMBL4282185 | 0.91 | CACNA1B (0.50) | CACNA1BNR1I2GAAHPGDRORC | |
| SCHEMBL4279230 | 0.91 | CACNA1B (0.50) | CACNA1BNR1I2GAAHPGDRORC | |
| SCHEMBL4279225 | 0.91 | CACNA1B (0.50) | CACNA1BNR1I2GAAHPGDRORC | |
| SCHEMBL4282188 | 0.91 | CACNA1B (0.50) | CACNA1BNR1I2GAAHPGDRORC | |
| Hydrochloric Acid SCHEMBL4284299 | 0.91 | CACNA1B (0.49) | CACNA1BNR1I2GAAHPGDRORC | |
| Hydrochloric Acid SCHEMBL4284297 | 0.91 | CACNA1B (0.49) | CACNA1BNR1I2GAAHPGDRORC | |
| Hydrochloric Acid SCHEMBL4278838 | 0.90 | CACNA1B (0.49) | CACNA1BNR1I2GAAHPGDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814851-B1 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO CELTIQUE SA (LU) | 2013-06-05 | — | — | EP | claimed |
| JP-2008516917-A | — | — | 2008-05-22 | — | — | JP | claimed |
| EP-1814851-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2007-08-08 | — | — | EP | claimed |
| WO-2006040181-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2006-04-20 | — | — | WO | claimed |
| EP-1814851-B1 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO CELTIQUE SA (LU) | 2013-06-05 | — | — | EP | disclosed |
| EP-1814851-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006040181-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2006-04-20 | — | — | WO | disclosed |