Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990197 | 0.83 | KDM4E (0.39) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL4993273 | 0.80 | HTT (0.41) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL29231745 | 0.74 | MAPT (0.43) | ALDH1A1HSD17B10TSHRKDM4EHPGD | |
| SCHEMBL4990517 | 0.73 | HPGD (0.43) | ALDH1A1TSHRKDM4EHPGDCYP2C9 | |
| SCHEMBL7959256 | 0.70 | GLA (0.34) | ALDH1A1KDM4EHPGDKMT2AGLA | |
| SCHEMBL3591480 | 0.69 | POLB (0.38) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL29658525 | 0.69 | HTT (0.56) | ALDH1A1HSD17B10TSHRKDM4EHPGD | |
| SCHEMBL19717030 | 0.69 | HTT (0.56) | ALDH1A1HSD17B10TSHRKDM4EHPGD | |
| SCHEMBL4740375 | 0.68 | KDM4E (0.51) | ALDH1A1HSD17B10TSHRKDM4EHPGD | |
| SCHEMBL19717463 | 0.65 | HTT (0.49) | ALDH1A1HSD17B10KDM4EHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |