⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16791395 | 0.56 | — | — | |
| SCHEMBL10616330 | 0.47 | — | — | |
| SCHEMBL10036543 | 0.45 | — | — | |
| SCHEMBL5318324 | 0.45 | — | — | |
| SCHEMBL8351884 | 0.41 | — | — | |
| SCHEMBL329462 | 0.37 | — | — | |
| SCHEMBL6718535 | 0.37 | — | — | |
| SCHEMBL605705 | 0.34 | — | — | |
| SCHEMBL1178 | 0.34 | — | — | |
| SCHEMBL444487 | 0.34 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549647-B1 | SUBSTITUTED C-IMIDAZO¬1,2-A|PYRIDIN-3-YL-METHYLAMINES | GRUENENTHAL GMBH (DE) | 2006-04-12 | — | — | EP | claimed |
| US-7345055-B2 | Substituted C-imidazo [1,2-α] pyridin-3-yl-methylamines | GRUENENTHAL GMBH (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7342025-B2 | Substituted C-imidazo[1,2-a]pyridin-3-yl-methylamines | GRUENENTHAL GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| EP-1549647-B1 | SUBSTITUTED C-IMIDAZO¬1,2-A|PYRIDIN-3-YL-METHYLAMINES | GRUENENTHAL GMBH (DE) | 2006-04-12 | — | — | EP | disclosed |
| EP-1549650-B1 | SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES | GRUENENTHAL GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20050239823-A1 | Substituted C-imidazo[1,2-a]pyridin-3yl-methylamines | GRUENENTHAL GMBH (DE) | 2005-10-27 | — | — | US | disclosed |
| US-20050239822-A1 | Substituted C-imiadazol[1,2-a] pyridin-3-yl-methylamines | GRUENENTHAL GMBH (DE) | 2005-10-27 | — | — | US | disclosed |
| EP-1549650-A1 | SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES | Grünenthal GmbH (DE) | 2005-07-06 | — | — | EP | disclosed |
| EP-1549647-A1 | SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES | Grünenthal GmbH (DE) | 2005-07-06 | — | — | EP | disclosed |
| US-20040142961-A1 | Utilization of substituted imidazo[1,2-a]-pyridine compounds in pharmaceutical formulations | GRUENENTHAL GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
| US-20040122044-A1 | Utilization of substituted imidazo [1,2-A]-pyridin-3-yl-amide and imidazo [1,2-A]-pyridin-3-yl-amine compounds in pharmaceutical formulations | GRUENENTHAL GMBH (DE) | 2004-06-24 | — | — | US | disclosed |
| WO-2004035578-A1 | SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES | Grünenthal GmbH (DE) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004033453-A1 | SUBSTITUTED C-IMIDAZO[1,2-A]PYRIDIN-3-YL-METHYLAMINES | Grünenthal GmbH (DE) | 2004-04-22 | — | — | WO | disclosed |
| US-6703404-B2 | NITRIC OXIDE SYNTHASE INHIBITORS | GRUENENTHAL GMBH (DE) | 2004-03-09 | — | — | US | disclosed |
| EP-1372647-A2 | USE OF SUBSTITUTED IMIDAZO 1,2-A]-PYRIDINE COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| EP-1372644-A2 | USE OF SUBSTITUTED IMIDAZO 1,2-A]-PYRIDINE-3-YL-AMIDE AND IMIDAZO 1,2-A]-PYRIDINE-3-YL-AMINE COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| EP-1218378-B1 | TERT.-BUTYL-(7-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-YL)-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20030022914-A1 | Tert.-butyl-(7-menthyl-imidazol [1,2-A] pyridin-3-yl)-amine derivatives | GRUENENTHAL GMBH . | 2003-01-30 | — | — | US | disclosed |
| WO-2002080911-A2 | USE OF SUBSTITUTED IMIDAZO[1,2-A]-PYRIDINE-3-YL-AMIDE AND IMIDAZO[1,2-A]-PYRIDINE-3-YL-AMINE COMPOUNDS AS MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Grünenthal GmbH (DE) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002080914-A2 | USE OF SUBSTITUTED IMIDAZO[1,2-A]-PYRIDINE COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2002-10-17 | — | — | WO | disclosed |