Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485923 | 0.85 | F2R (0.73) | F2RCYP2C19SMN1; SMN2TSHR | |
| SCHEMBL486326 | 0.82 | F2R (0.70) | F2RCYP2C19SMN1; SMN2 | |
| SCHEMBL661950 | 0.81 | F2R (1.00) | F2RCYP2C19SMN1; SMN2 | |
| SCHEMBL485965 | 0.81 | F2R (1.00) | F2RCYP2C19 | |
| SCHEMBL485814 | 0.79 | F2R (0.83) | F2RCYP2C19 | |
| SCHEMBL486312 | 0.79 | F2R (0.75) | F2R | |
| SCHEMBL662954 | 0.78 | F2R (0.80) | F2RCYP2C19 | |
| SCHEMBL16579598 | 0.76 | F2R (0.81) | F2RSMN1; SMN2 | |
| SCHEMBL486250 | 0.76 | F2R (0.65) | F2RCYP2C19SMN1; SMN2TSHR | |
| SCHEMBL486000 | 0.75 | HPGD (0.42) | F2RHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-B1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER IP GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108608-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-30 | — | — | WO | disclosed |