SCHEMBL4865577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4865140	0.86	EGFR (0.60)	EGFRERBB2AURKAGAK
	SCHEMBL24377	0.86	EGFR (0.66)	EGFRKDREPHB4ERBB2CLK1
	SCHEMBL9910688	0.85	EGFR (0.69)	EGFRKDREPHB4ERBB2GAK
	SCHEMBL26876	0.84	EGFR (0.83)	EGFRKDREPHB4ERBB2CLK1
	SCHEMBL29362232	0.84	EGFR (0.83)	EGFRKDREPHB4ERBB2CLK1
	SCHEMBL2255348	0.83	EGFR (0.69)	EGFRKDREPHB4ERBB2AURKA
	Hydrochloric Acid SCHEMBL28101874	0.83	EGFR (0.81)	EGFRKDREPHB4ERBB2CLK1
	Water SCHEMBL28549003	0.83	EGFR (0.81)	EGFRKDREPHB4ERBB2CLK1
	SCHEMBL9910672	0.83	EGFR (0.86)	EGFRKDREPHB4ERBB2GAK
	SCHEMBL9910674	0.83	EGFR (0.71)	EGFRKDREPHB4ERBB2CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.