Methoxyfenozide

Methoxyfenozide

SCHEMBL4866865

CCc1ccc(C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C)cc1.COc1cccc(C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C)c1C

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 7/20 0.81
CYP3A4 P08684 1/20 0.72
HPGD P15428 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxyfenozide SCHEMBL27595 0.90 ABCB1 (1.00) ABCB1
Methoxyfenozide SCHEMBL27901977 0.89 ABCB1 (0.98) ABCB1
Methoxyfenozide SCHEMBL19032820 0.88 ABCB1 (0.63) ABCB1CYP3A4HPGDSMN1; SMN2
SCHEMBL8384583 0.85 ABCB1 (0.72) ABCB1CYP3A4HPGDSMN1; SMN2
SCHEMBL5058384 0.85 ABCB1 (0.86) ABCB1CYP3A4
Methoxyfenozide SCHEMBL3938501 0.85 ABCB1 (0.78) ABCB1
Tebufenozide SCHEMBL64845 0.85 ABCB1 (1.00) ABCB1CYP3A4HPGDSMN1; SMN2
SCHEMBL5057274 0.84 ABCB1 (0.88) ABCB1
SCHEMBL64477 0.84 ABCB1 (0.77) ABCB1CYP3A4
SCHEMBL29381163 0.84 ABCB1 (0.77) ABCB1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10694749-B2 Insecticide formulation WELLMARK INTERNATIONAL (US) 2020-06-30 US disclosed
US-10645932-B2 Extended release formulation WELLMARK INTERNATIONAL (US) 2020-05-12 US disclosed
US-10645931-B2 Extended release formulation WELLMARK INTERNATIONAL (US) 2020-05-12 US disclosed
EP-3471546-A1 INSECTICIDE FORMULATION Wellmark International (US) 2019-04-24 EP disclosed
US-20180325116-A1 EXTENDED RELEASE FORMULATION WELLMARK INTERNATIONAL (US) 2018-11-15 US disclosed
WO-2018111685-A1 EXTENDED RELEASE FORMULATION WELLMARK INTERNATIONAL (US) 2018-06-21 WO disclosed
US-20180168162-A1 EXTENDED RELEASE FORMULATION WELLMARK INTERNATIONAL (US) 2018-06-21 US disclosed
WO-2017222885-A1 INSECTICIDE FORMULATION WELLMARK INTERNATIONAL (US) 2017-12-28 WO disclosed
US-20170360047-A1 INSECTICIDE FORMULATION WELLMARK INTERNATIONAL (US) 2017-12-21 US disclosed
EP-2956005-A2 MINERAL FEED-THROUGH FORMULATION Wellmark International (US) 2015-12-23 EP disclosed
US-20140234386-A1 MINERAL FEED-THROUGH FORMULATION WELLMARK INTERNATIONAL 2014-08-21 US disclosed
WO-2014127022-A2 MINERAL FEED-THROUGH FORMULATION WELLMARK INTERNATIONAL (US) 2014-08-21 WO disclosed
US-7348019-B1 Stabilized block pesticide compositions WELLMARK INTERNATIONAL (US) 2008-03-25 US disclosed
US-20070207177-A1 METHODS OF PREPARING PESTICIDE FORMULATIONS AND THEIR METHODS OF USE WELLMARK INTERNATIONAL CENTRAL LIFE SCIENCES (US) 2007-09-06 US disclosed
US-7238365-B1 Including a pesticide selected from methoprene, hydroprene, kinoprene, fenoxycarb, pyriproxifen, cyromazine, dimilin, novaluron or mixture, a hydrophobic agents such as fat, vegetable oil and mineral oil, a surfactant, a carbohydrate as uniformity extending agent and a gum; stability WELLMARK INTERNATIONAL (US) 2007-07-03 US disclosed
US-7163687-B1 Stabilized pesticide compositions WELLMARK INTERNATIONAL (US) 2007-01-16 US disclosed