Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697448 | 1.00 | RARB (0.61) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL12972983 | 1.00 | RARB (0.61) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL2356972 | 1.00 | RARB (0.61) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL2356412 | 1.00 | RARB (0.61) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL1792760 | 1.00 | RARB (0.61) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL2357155 | 0.98 | CYP2D6 (0.59) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL7330936 | 0.94 | CYP2D6 (0.63) | RARBCYP3A4CYP2D6LTA4HCYP19A1 | |
| SCHEMBL1102341 | 0.94 | NR5A1 (0.66) | RARBNR5A1LTA4HTP53TSHR | |
| SCHEMBL8215140 | 0.94 | NR5A1 (0.66) | RARBNR5A1LTA4HTP53TSHR | |
| SCHEMBL6740617 | 0.94 | NR5A1 (0.66) | RARBNR5A1LTA4HTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10923662-B2 | Fluoroalkylfluorene derivatives | LOMOX LIMITED (GB) | 2021-02-16 | — | — | US | disclosed |
| EP-3131898-B1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LTD (GB) | 2020-03-18 | — | — | EP | disclosed |
| US-10084137-B2 | Fluoroalkylfluorene derivatives | LOMOX LIMITED (GB) | 2018-09-25 | — | — | US | disclosed |
| US-20180261771-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2018-09-13 | — | — | US | disclosed |
| EP-3131898-A1 | FLUOROALKYLFLUORENE DERIVATIVES | Lomox Limited (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2017-02-02 | — | — | US | disclosed |
| WO-2015159098-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2015-10-22 | — | — | WO | disclosed |
| US-7851074-B2 | Organic electroluminescent display device and chemical compounds for liquid crystals | TOHOKU PIONEER CORPORATION (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20090058277-A1 | Organic Electroluminescent Display Device and Chemical Compounds for Liquid Crystals | TOHOKU PIONEER CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-7351452-B2 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2008-04-01 | — | — | US | disclosed |
| EP-0360042-A1 | p-Terphenyl derivatives and liquid crystalline compositions | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0201578-B1 | ALPHA-HYDROXY CARBOXYLIC ACID DERIVATIVES SUITABLE FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1989-11-02 | — | — | EP | disclosed |
| US-4873019-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-10 | — | — | US | disclosed |
| US-4852977-A | 19 -hydroxy carboxylic acid derivatives suitable for use in liquid crystal materials and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0261160-A1 | Alicyclic compounds. | MERCK PATENT GMBH (DE) | 1988-03-30 | — | — | EP | disclosed |
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005599-A1 | TERTIARY ALCOHOLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-24 | — | — | WO | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |
| EP-0201578-A1 | ALPHA-HYDROXY CARBOXYLIC ACID DERIVATIVES SUITABLE FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES. | SECR DEFENCE BRIT (GB) | 1986-11-20 | — | — | EP | disclosed |
| WO-1986002938-A1 | ALPHA-HYDROXY CARBOXYLIC ACID DERIVATIVES SUITABLE FOR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1986-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10084137-B2 | Fluoroalkylfluorene derivatives | FLNB, AFF2, EFHD2 | RARB 2518/4885NR5A1 4015/4885CYP3A4 953/4885 |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | FLNB, AFF2, EFHD2 | RARB 2518/4885NR5A1 4015/4885CYP3A4 953/4885 |
| US-10923662-B2 | Fluoroalkylfluorene derivatives | FLNB, AFF2, EFHD2 | RARB 2518/4885NR5A1 4015/4885CYP3A4 953/4885 |
| US-20180261771-A1 | FLUOROALKYLFLUORENE DERIVATIVES | FLNB, AFF2, EFHD2 | RARB 2518/4885NR5A1 4015/4885CYP3A4 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.