⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909169 | 0.93 | — | — | |
| Chloroform SCHEMBL2074157 | 0.72 | — | — | |
| SCHEMBL11002848 | 0.72 | — | — | |
| SCHEMBL91 | 0.57 | — | — | |
| Hno SCHEMBL27548960 | 0.57 | — | — | |
| SCHEMBL10886783 | 0.51 | — | — | |
| Methane SCHEMBL2045187 | 0.51 | — | — | |
| Fluoride SCHEMBL6881674 | 0.51 | — | — | |
| Water SCHEMBL369703 | 0.51 | — | — | |
| SCHEMBL365541 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030960-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2024-02-08 | — | — | WO | disclosed |
| EP-1511725-B1 | 24-SULFOXIMINE VITAMIN D3 COMPOUNDS | UNIV JOHNS HOPKINS (US) | 2012-02-01 | — | — | EP | disclosed |
| US-7973024-B2 | 24-sulfoximine vitamin D3 compounds | Cyctochroma Inc. (CA) | 2011-07-05 | — | — | US | disclosed |
| US-20060217353-A1 | 24-sulfoximine vitamin D3 compounds | CYTOCHROMA INC. (CA) | 2006-09-28 | — | — | US | disclosed |
| US-7101865-B2 | 24-sulfoximine vitamin D3 compounds | CYTOCHROMA INC. (CA) | 2006-09-05 | — | — | US | disclosed |
| EP-1511725-A1 | 24-SULFOXIMINE VITAMIN D sb 3 /sb COMPOUNDS | Johns Hopkins University (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20040038949-A1 | 24-sulfoximine vitamin D3 compounds | JOHNS HOPKINS UNIVERSITY | 2004-02-26 | — | — | US | disclosed |
| WO-2003106411-A1 | 24-SULFOXIMINE VITAMIN D3 COMPOUNDS | JOHNS HOPKINS UNIVERSITY (US) | 2003-12-24 | — | — | WO | disclosed |